Varaico: Literature-Extracted Genetic Variants

Gene:PRKDC
Variant:p.K3753R
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PRKDC

NM_006904.7:p.K3753R

Associated Papers

DNA-PKcs suppresses illegitimate chromosome rearrangements.

Wang J et al.

Nucleic Acids Research, 2024

Comparative analysis of basal and etoposide-induced alterations in gene expression by DNA-PKcs kinase activity.

Ali SI et al.

Frontiers in Genetics, 2024

Efficient high-precision homology-directed repair-dependent genome editing by HDRobust.

Riesenberg S et al.

Nature Methods, 2023

Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development.

Mora-Bermúdez F et al.

Science Advances, 2022

Reduced purine biosynthesis in humans after their divergence from Neandertals.

Stepanova V et al.

Elife, 2021

DNA-PKcs promotes chromatin decondensation to facilitate initiation of the DNA damage response.

Lu H et al.

Nucleic Acids Research, 2019

Restoration of ATM Expression in DNA-PKcs-Deficient Cells Inhibits Signal End Joining.

Neal JA et al.

Journal of Immunology (baltimore, Md. : 1950), 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."