Varaico: Literature-Extracted Genetic Variants

Gene:PRKDC
Variant:p.T2638A
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PRKDC

NM_006904.7:p.T2638A

Associated Papers

Differential radiosensitivity phenotypes of DNA-PKcs mutations affecting NHEJ and HRR systems following irradiation with gamma-rays or very low fluences of alpha particles.

Lin YF et al.

Plos One, 2014

DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM).

Zhou Y et al.

The Journal of Biological Chemistry, 2013

Telomere dysfunction and DNA-PKcs deficiency: characterization and consequence.

Williams ES et al.

Cancer Research, 2009

Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends.

Block WD et al.

Nucleic Acids Research, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."