Varaico: Literature-Extracted Genetic Variants

Gene:PRKN
Variant:p.C352G
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PRKN

NM_004562.3:p.C352G

Associated Papers

Role of Optineurin in the Mitochondrial Dysfunction: Potential Implications in Neurodegenerative Diseases and Cancer.

Weil R et al.

Frontiers in Immunology, 2018

The ubiquitin signal and autophagy: an orchestrated dance leading to mitochondrial degradation.

Yamano K et al.

Embo Reports, 2016

Site-specific Interaction Mapping of Phosphorylated Ubiquitin to Uncover Parkin Activation.

Yamano K et al.

The Journal of Biological Chemistry, 2015

The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons.

Koyano F et al.

Genes to Cells : Devoted to Molecular & Cellular Mechanisms, 2013

Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation.

Iguchi M et al.

The Journal of Biological Chemistry, 2013

Mitochondrial hexokinase HKI is a novel substrate of the Parkin ubiquitin ligase.

Okatsu K et al.

Biochemical and Biophysical Research Communications, 2012

p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria.

Okatsu K et al.

Genes to Cells : Devoted to Molecular & Cellular Mechanisms, 2010

Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro.

Matsuda N et al.

The Journal of Biological Chemistry, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."