Varaico: Literature-Extracted Genetic Variants

Gene:PRKN
Variant:p.K349R
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PRKN

NM_004562.3:p.K349R

Associated Papers

Ubiquitination at the lysine 27 residue of the Parkin ubiquitin-like domain is suggestive of a new mechanism of Parkin activation.

Liu JY et al.

Human Molecular Genetics, 2022

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy.

Sun X et al.

Acta Pharmaceutica Sinica. B, 2022

Covalent ISG15 conjugation positively regulates the ubiquitin E3 ligase activity of parkin.

Im E et al.

Open Biology, 2016

Neddylation positively regulates the ubiquitin E3 ligase activity of parkin.

Um JW et al.

Journal of Neuroscience Research, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."