Varaico: Literature-Extracted Genetic Variants

Gene:PRKN
Variant:p.V324A
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PRKN

NM_004562.3:p.V324A

Associated Papers

Genetic predispositions of Parkinson's disease revealed in patient-derived brain cells.

Tran J et al.

Npj Parkinson's Disease, 2020

Opportunities and challenges for the use of induced pluripotent stem cells in modelling neurodegenerative disease.

Wu YY et al.

Open Biology, 2019

HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons.

Kishinevsky S et al.

Nature Communications, 2018

Generating Late-Onset Human iPSC-Based Disease Models by Inducing Neuronal Age-Related Phenotypes through Telomerase Manipulation.

Vera E et al.

Cell Reports, 2016

Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation.

Chung SY et al.

Stem Cell Reports, 2016

Human iPSC-based modeling of late-onset disease via progerin-induced aging.

Miller JD et al.

Cell Stem Cell, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."