Varaico: Literature-Extracted Genetic Variants

Gene:PRKN
Variant:p.C323S
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PRKN

NM_004562.3:p.C323S

Associated Papers

Canonical and alternate mechanisms that regulate ubiquitylation by the E3 ligase parkin.

Basilone NT et al.

Biochemical Society Transactions, 2025

DJ-1 is indispensable for the S-nitrosylation of Parkin, which maintains function of mitochondria.

Ozawa K et al.

Scientific Reports, 2020

Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation.

Iguchi M et al.

The Journal of Biological Chemistry, 2013

S-nitrosylation regulates mitochondrial quality control via activation of parkin.

Ozawa K et al.

Scientific Reports, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."