Varaico: Literature-Extracted Genetic Variants

Gene:PRKN
Variant:p.E321A
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PRKN

NM_004562.3:p.E321A

Associated Papers

Structural basis for the pathogenicity of parkin catalytic domain mutants.

Wagner JP et al.

The Journal of Biological Chemistry, 2025

39631693 (PubMed )
Supplement: mmc1.pdf

A mechanistic review of Parkin activation.

Gundogdu M et al.

Biochimica Et Biophysica Acta. General Subjects, 2021

Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.

Kumar A et al.

Nature Structural & Molecular Biology, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."