Associated Papers
WES-Based Screening of a Swedish Patient Series with Parkinson's Disease.
Kafantari E et al.
Genes, 2025
Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W.
Bustillos BA et al.
Cells, 2024
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway.
Su Q et al.
Acta Pharmacologica Sinica, 2024
Interplay between α-synuclein and parkin genes: Insights of Parkinson's disease.
Sharma K et al.
Molecular Biology Reports, 2024
Genotype-phenotype correlation in PRKN-associated Parkinson's disease.
Menon PJ et al.
Npj Parkinson's Disease, 2024
High-content phenotypic screen to identify small molecule enhancers of Parkin-dependent ubiquitination and mitophagy.
Tufi R et al.
Slas Discovery : Advancing Life Sciences R & D, 2023
Systematic Functional Analysis of PINK1 and PRKN Coding Variants.
Broadway BJ et al.
Cells, 2022
Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches.
Tsefou E et al.
The Biochemical Journal, 2021
Deep resequencing identifies candidate functional genes in leprosy GWAS loci.
Fava VM et al.
Plos Neglected Tropical Diseases, 2021
Spatially interacting phosphorylation sites and mutations in cancer.
Huang KL et al.
Nature Communications, 2021
Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons.
Schwartzentruber A et al.
Scientific Reports, 2020
Deep brain stimulation for monogenic Parkinson's disease: a systematic review.
Kuusimäki T et al.
Journal of Neurology, 2020
Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson's disease.
Fava VM et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019
Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma.
Lin DC et al.
Cancer Research, 2015
A recurrent mutation in PARK2 is associated with familial lung cancer.
Xiong D et al.
American Journal of Human Genetics, 2015
Genotype and phenotype in Parkinson's disease: lessons in heterogeneity from deep brain stimulation.
Angeli A et al.
Movement Disorders : Official Journal of the Movement Disorder Society, 2013
Creation of an open-access, mutation-defined fibroblast resource for neurological disease research.
Wray S et al.
Plos One, 2012
Parkin enhances the expression of cyclin-dependent kinase 6 and negatively regulates the proliferation of breast cancer cells.
Tay SP et al.
The Journal of Biological Chemistry, 2010
Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies.
Veeriah S et al.
Nature Genetics, 2010