Varaico: Literature-Extracted Genetic Variants

Gene:PRKN
Variant:p.N273K
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PRKN

NM_004562.3:p.N273K

Associated Papers

Computational Study of the Activation Mechanism of Wild-Type Parkin and Its Clinically Relevant Mutant.

Cinviz ZN et al.

Acs Chemical Neuroscience, 2025

In Silico Investigation of Parkin-Activating Mutations Using Simulations and Network Modeling.

Islam NN et al.

Biomolecules, 2024

Structure-based design and characterization of Parkin-activating mutations.

Stevens MU et al.

Life Science Alliance, 2023

36941054 (PubMed )
Supplement: LSA-2022-01419_TableS1.xlsx › Sheet1

Structural basis for feedforward control in the PINK1/Parkin pathway.

Sauvé V et al.

The Embo Journal, 2022

35491809 (PubMed )
Supplement: EMBJ-41-e109460-s003.pdf

Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation.

Tang MY et al.

Nature Communications, 2017

A Ubl/ubiquitin switch in the activation of Parkin.

Sauvé V et al.

The Embo Journal, 2015

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