Varaico: Literature-Extracted Genetic Variants

Gene:PRKN
Variant:p.N254S
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PRKN

NM_004562.3:p.N254S

Associated Papers

Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway.

Su Q et al.

Acta Pharmacologica Sinica, 2024

Single nucleotide variants in lung cancer.

Tian X et al.

Chinese Medical Journal Pulmonary and Critical Care Medicine, 2024

Somatic and germline mutations in the tumor suppressor gene PARK2 impair PINK1/Parkin-mediated mitophagy in lung cancer cells.

Zhang ZL et al.

Acta Pharmacologica Sinica, 2020

Parkin and mitophagy in cancer.

Bernardini JP et al.

Oncogene, 2017

Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma.

Lin DC et al.

Cancer Research, 2015

Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies.

Veeriah S et al.

Nature Genetics, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."