Varaico: Literature-Extracted Genetic Variants

Gene:PRKN
Variant:p.S198A
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PRKN

NM_004562.3:p.S198A

Associated Papers

Parkinson's disease-linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons.

Song P et al.

Neuron, 2023

Phosphorylation of Parkin at serine 131 by p38 MAPK promotes mitochondrial dysfunction and neuronal death in mutant A53T α-synuclein model of Parkinson's disease.

Chen J et al.

Cell Death & Disease, 2018

Dyrk1A phosphorylates parkin at Ser-131 and negatively regulates its ubiquitin E3 ligase activity.

Im E et al.

Journal of Neurochemistry, 2015

Interleukin 10 rs1800872 T>G polymorphism was associated with an increased risk of esophageal cancer in a Chinese population.

Sun JM et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."