Associated Papers
PTMD 2.0: an updated database of disease-associated post-translational modifications.
Huang X et al.
Nucleic Acids Research, 2025
39329270 (PubMed )
Supplement: gkae850_supplemental_files.zip › Table_S2.xlsx › Table_S2
Phosphorylation of Parkin at serine 131 by p38 MAPK promotes mitochondrial dysfunction and neuronal death in mutant A53T α-synuclein model of Parkinson's disease.
Chen J et al.
Cell Death & Disease, 2018
Dyrk1A phosphorylates parkin at Ser-131 and negatively regulates its ubiquitin E3 ligase activity.
Im E et al.
Journal of Neurochemistry, 2015
Combined kinase inhibition modulates parkin inactivation.
Rubio de la Torre E et al.
Human Molecular Genetics, 2009
Synphilin-1 isoforms in Parkinson's disease: regulation by phosphorylation and ubiquitylation.
Szargel R et al.
Cellular and Molecular Life Sciences : Cmls, 2008
Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation.
Avraham E et al.
The Journal of Biological Chemistry, 2007
Parkin phosphorylation and modulation of its E3 ubiquitin ligase activity.
Yamamoto A et al.
The Journal of Biological Chemistry, 2005
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