Varaico: Literature-Extracted Genetic Variants

Gene:PRKN
Variant:p.V70A
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PRKN

NM_004562.3:p.V70A

Associated Papers

Genomic Profiling of Cardiac Angiosarcoma Reveals Novel Targetable KDR Variants, Recurrent MED12 Mutations, and a High Burden of Germline POT1 Alterations.

Odintsov I et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2025

39820259 (PubMed )
Supplement: ccr-24-3277_supplementary_table_s1_suppts1.xlsx › SNV_INDEL

Capturing the catalytic intermediates of parkin ubiquitination.

Connelly EM et al.

Proceedings of the National Academy of Sciences of the United States of America, 2024

Interaction between RING1 (R1) and the Ubiquitin-like (UBL) Domains Is Critical for the Regulation of Parkin Activity.

Ham SJ et al.

The Journal of Biological Chemistry, 2016

Autoregulation of Parkin activity through its ubiquitin-like domain.

Chaugule VK et al.

The Embo Journal, 2011

The essential functions of NEDD8 are mediated via distinct surface regions, and not by polyneddylation in Schizosaccharomyces pombe.

Girdwood D et al.

Plos One, 2011

21655279 (PubMed )
Supplement: pone.0020089.s001.xls › Sheet1

The human Cdc34 carboxyl terminus contains a non-covalent ubiquitin binding activity that contributes to SCF-dependent ubiquitination.

Choi YS et al.

The Journal of Biological Chemistry, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."