Varaico: Literature-Extracted Genetic Variants

Gene:PRKN
Variant:p.E28K
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PRKN

NM_004562.3:p.E28K

Associated Papers

PROTAC repurposing uncovers a noncanonical binding surface that mediates chemical degradation of nuclear receptors.

Huber AD et al.

Nature Communications, 2025

41198675 (PubMed )
Supplement: 41467_2025_64773_MOESM12_ESM.xlsx › Supplementary_Data_10

Link between Parkinson's disease and melanoma: insights into the influence of the PARK gene family.

Wu J et al.

Frontiers in Oncology, 2025

Therapeutic potential of Parkin and its regulation in Parkinson's disease.

Safreena N et al.

Biochemical Pharmacology, 2024

The Bifunctional Dimer Caffeine-Indan Attenuates α-Synuclein Misfolding, Neurodegeneration and Behavioral Deficits after Chronic Stimulation of Adenosine A1 Receptors.

Jakova E et al.

International Journal of Molecular Sciences, 2024

Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance.

Perales-Linares R et al.

Cancer Research, 2023

Study of the Effects of Nicotine and Caffeine for the Treatment of Parkinson's Disease.

Biswas S et al.

Applied Biochemistry and Biotechnology, 2023

An empirical pipeline for personalized diagnosis of Lafora disease mutations.

Brewer MK et al.

Iscience, 2021

Structural analysis of the effects of mutations in Ubl domain of Parkin leading to Parkinson's disease.

Biswas S et al.

Gene, 2020

Algorithmic assessment of missense mutation severity in the Von-Hippel Lindau protein.

Fields FR et al.

Plos One, 2020

33151962 (PubMed )
Supplement: pone.0234100.s007.xlsx › Unweighted_ClinVar_Muts

Parkin Somatic Mutations Link Melanoma and Parkinson's Disease.

Levin L et al.

Journal of Genetics and Genomics = Yi Chuan Xue Bao, 2016

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update.

Nuytemans K et al.

Human Mutation, 2010

20506312 (PubMed )
Supplement: humu0031-0763-SD1.pdf

Genotypic analysis of the protease and reverse transcriptase of non-B HIV type 1 clinical isolates from naïve and treated subjects.

Monno L et al.

Antiviral Research, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."