Varaico: Literature-Extracted Genetic Variants

Gene:PRKN
Variant:p.S22R
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PRKN

NM_004562.3:p.S22R

Associated Papers

Structural ubiquitin contributes to K48 linkage specificity of the HECT ligase Tom1.

Warner K et al.

Cell Reports, 2025

Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation.

Middleton AJ et al.

Structure (london, England : 1993), 2023

Assessing the Direct Binding of Ark-Like E3 RING Ligases to Ubiquitin and Its Implication on Their Protein Interaction Network.

Mintis DG et al.

Molecules (basel, Switzerland), 2020

Critical Role of the UBL Domain in Stimulating the E3 Ubiquitin Ligase Activity of UHRF1 toward Chromatin.

Foster BM et al.

Molecular Cell, 2018

Auto-ubiquitination of Mdm2 enhances its substrate ubiquitin ligase activity.

Ranaweera RS et al.

The Journal of Biological Chemistry, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."