Associated Papers
PRMT5-mediated arginine methylation stabilizes GPX4 to suppress ferroptosis in cancer.
Fan Y et al.
Nature Cell Biology, 2025
ROS inhibits RORα degradation by decreasing its arginine methylation in liver cancer.
Im H et al.
Cancer Science, 2023
PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.
Yin S et al.
Nature Communications, 2021
Transcriptional perturbation of protein arginine methyltransferase-5 exhibits MTAP-selective oncosuppression.
Busacca S et al.
Scientific Reports, 2021
PRMT5 Regulates DNA Repair by Controlling the Alternative Splicing of Histone-Modifying Enzymes.
Hamard PJ et al.
Cell Reports, 2018
SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth.
Tamiya H et al.
The Journal of Clinical Investigation, 2018
Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5.
Mavrakis KJ et al.
Science (new York, N.y.), 2016
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