Associated Papers
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6.
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A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6.
Shen Y et al.
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Skeletal muscle-specific Prmt1 deletion causes muscle atrophy via deregulation of the PRMT6-FOXO3 axis.
Choi S et al.
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A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases.
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Acs Chemical Biology, 2016
Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy.
Scaramuzzino C et al.
Neuron, 2015
Automethylation of protein arginine methyltransferase 6 (PRMT6) regulates its stability and its anti-HIV-1 activity.
Singhroy DN et al.
Retrovirology, 2013
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