Varaico: Literature-Extracted Genetic Variants

Gene:PRNP
Variant:p.M112T
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PRNP

NM_000311.5:p.M112T

Associated Papers

Mapping PRNP Polymorphisms in Portuguese Serra da Estrela Ovine Populations: Insights into Scrapie Susceptibility and Farm Animal Improvement.

Rodrigues S et al.

Animals : an Open Access Journal From Mdpi, 2025

Genetic variability of the prion protein gene (PRNP) in thin-tailed and fat-tailed sheep.

Wicaksono A et al.

Open Veterinary Journal, 2025

Five novel PRNP gene polymorphisms and their potential effect on Scrapie susceptibility in three native Ethiopian sheep breeds.

Teferedegn EY et al.

Bmc Veterinary Research, 2020

Potential scrapie-associated polymorphisms of the prion protein gene (PRNP) in Korean native black goats.

Kim SK et al.

Scientific Reports, 2019

In silico investigation of the prion protein glycosylation profiles in relation to scrapie disease resistance in domestic sheep (Ovis aries).

Uslupehlivan M et al.

Molecular and Cellular Probes, 2018

Biodiversity and selection for scrapie resistance in sheep: genetic polymorphism in eight breeds of Algeria.

Djaout A et al.

Journal of Genetics, 2018

Allelic variants of PRNP in 16 Chinese local sheep breeds.

Lan Z et al.

Archives of Virology, 2014

Polymorphisms at amino acid residues 141 and 154 influence conformational variation in ovine PrP.

Yang S et al.

Biomed Research International, 2014

Novel polymorphisms in ovine prion protein gene.

Meydan H et al.

Animal Genetics, 2013

Prion protein gene variability in Spanish goats. Inference through susceptibility to classical scrapie strains and pathogenic distribution of peripheral PrP(sc.).

Acín C et al.

Plos One, 2013

Prion protein coding gene (PRNP) variability in sheep from Turkey and Iran.

Frootan F et al.

Biochemical Genetics, 2012

Characterization of PRNP and SPRN coding regions from atypical scrapie cases diagnosed in Poland.

Piestrzyńska-Kajtoch A et al.

Molecular Biology Reports, 2012

Detection of four novel polymorphisms in PrP gene of Pakistani sheep (Damani and Hashtnagri) and goats (Kamori and Local Hairy) breeds.

Hussain A et al.

Virology Journal, 2011

Ovine reference materials and assays for prion genetic testing.

Heaton MP et al.

Bmc Veterinary Research, 2010

p.Asn176Lys and p.Met137Thr dimorphisms of the PRNP gene significantly decrease the susceptibility to classical scrapie in ARQ/ARQ sheep.

Maestrale C et al.

Animal Genetics, 2009

Scrapie resistance in ARQ sheep.

Laegreid WW et al.

Journal of Virology, 2008

Polymorphisms of the prion protein gene in sheep of Inner Mongolia, China.

Wang Y et al.

Virus Genes, 2008

Copper-induced structural changes in the ovine prion protein are influenced by a polymorphism at codon 112.

Yang S et al.

Biochimica Et Biophysica Acta, 2008

Prion protein alleles showing a protective effect on the susceptibility of sheep to scrapie and bovine spongiform encephalopathy.

Vaccari G et al.

Journal of Virology, 2007

Prion protein gene (PRNP) polymorphisms in Xinjiang local sheep breeds in China.

Lan Z et al.

Archives of Virology, 2006

PRNP polymorphisms in Chinese ovine, caprine and bovine breeds.

Zhang L et al.

Animal Genetics, 2004

Prion gene sequence variation within diverse groups of U.S. sheep, beef cattle, and deer.

Heaton MP et al.

Mammalian Genome : Official Journal of the International Mammalian Genome Society, 2003

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