Varaico: Literature-Extracted Genetic Variants

Gene:PRNP
Variant:p.A116G
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PRNP

NM_000311.5:p.A116G

Associated Papers

Spatial and Temporal Patterns of Prion Gene Variation Are Consistent With a Response to Chronic Wasting Disease-Induced Selection in Wild White-Tailed Deer.

Bubac CM et al.

Ecology and Evolution, 2025

Effect of primary structural variation on cervid prion protein in flexibility, stability, and spontaneous misfolding propensity.

Díaz-Domínguez CM et al.

Neurobiology of Disease, 2025

White-Tailed Deer Prion Protein Gene Variability Suggests Selection Against Chronic Wasting Disease in Canada's Prairies.

Pilot W et al.

Viruses, 2025

Identification of the Highly Polymorphic Prion Protein Gene (PRNP) in Frogs (Rana dybowskii).

Han CS et al.

Animals : an Open Access Journal From Mdpi, 2025

Estimating sequence diversity of prion protein gene (PRNP) in Portuguese populations of two cervid species: red deer and fallow deer.

Pereira JC et al.

Prion, 2023

Novel polymorphisms in the prion protein gene (PRNP) and stability of the resultant prion protein in different horse breeds.

Sola D et al.

Veterinary Research, 2023

Heterozygosity for cervid S138N polymorphism results in subclinical CWD in gene-targeted mice and progressive inhibition of prion conversion.

Arifin MI et al.

Proceedings of the National Academy of Sciences of the United States of America, 2023

Transmission of cervid prions to humanized mice demonstrates the zoonotic potential of CWD.

Hannaoui S et al.

Acta Neuropathologica, 2022

First report of structural characteristics and polymorphisms of the prion protein gene in raccoon dogs: The possibility of prion disease-resistance.

Jo WS et al.

Frontiers in Veterinary Science, 2022

New and distinct chronic wasting disease strains associated with cervid polymorphism at codon 116 of the Prnp gene.

Hannaoui S et al.

Plos Pathogens, 2021

Cervid Prion Protein Polymorphisms: Role in Chronic Wasting Disease Pathogenesis.

Arifin MI et al.

International Journal of Molecular Sciences, 2021

Genetic Factors in Mammalian Prion Diseases.

Mead S et al.

Annual Review of Genetics, 2019

Low sequence diversity of the prion protein gene (PRNP) in wild deer and goat species from Spain.

Pitarch JL et al.

Veterinary Research, 2018

Prion gene sequence variation within diverse groups of U.S. sheep, beef cattle, and deer.

Heaton MP et al.

Mammalian Genome : Official Journal of the International Mammalian Genome Society, 2003

Prion sequence polymorphisms and chronic wasting disease resistance in Illinois white-tailed deer (Odocoileus virginianus).

Kelly AC et al.

Prion, 0

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