Varaico: Literature-Extracted Genetic Variants

Gene:PRNP
Variant:p.D147N
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PRNP

NM_000311.5:p.D147N

Associated Papers

Salt bridges in prion proteins are necessary for high-affinity binding to the monoclonal antibody T2.

Sasamori E et al.

Biophysical Chemistry, 2011

Molecular dynamics as an approach to study prion protein misfolding and the effect of pathogenic mutations.

van der Kamp MW et al.

Topics in Current Chemistry, 2011

Searching for factors that distinguish disease-prone and disease-resistant prions via sequence analysis.

Kedarisetti KD et al.

Bioinformatics and Biology Insights, 2008

Molecular mechanism for low pH triggered misfolding of the human prion protein.

DeMarco ML et al.

Biochemistry, 2007

The role of helix 1 aspartates and salt bridges in the stability and conversion of prion protein.

Speare JO et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."