Varaico: Literature-Extracted Genetic Variants

Gene:PRNP
Variant:p.N159D
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PRNP

NM_000311.5:p.N159D

Associated Papers

The First Genetic Characterization of the SPRN Gene in Pekin Ducks (Anas platyrhynchos domesticus).

Nguyen TT et al.

Animals : an Open Access Journal From Mdpi, 2024

Arg177 and Asp159 from dog prion protein slow liquid-liquid phase separation and inhibit amyloid formation of human prion protein.

Li XN et al.

The Journal of Biological Chemistry, 2023

Drosophila melanogaster as a model to study autophagy in neurodegenerative diseases induced by proteinopathies.

Santarelli S et al.

Frontiers in Neuroscience, 2023

Intrinsic determinants of prion protein neurotoxicity in Drosophila: from sequence to (dys)function.

Cembran A et al.

Frontiers in Molecular Neuroscience, 2023

New Drosophila models to uncover the intrinsic and extrinsic factors that mediate the toxicity of the human prion protein.

Myers RR et al.

Disease Models & Mechanisms, 2022

Insight From Animals Resistant to Prion Diseases: Deciphering the Genotype - Morphotype - Phenotype Code for the Prion Protein.

Myers R et al.

Frontiers in Cellular Neuroscience, 2020

A Single Amino Acid Substitution, Found in Mammals with Low Susceptibility to Prion Diseases, Delays Propagation of Two Prion Strains in Highly Susceptible Transgenic Mouse Models.

Otero A et al.

Molecular Neurobiology, 2019

D159 and S167 are protective residues in the prion protein from dog and horse, two prion-resistant animals.

Sanchez-Garcia J et al.

Neurobiology of Disease, 2018

A single amino acid (Asp159) from the dog prion protein suppresses the toxicity of the mouse prion protein in Drosophila.

Sanchez-Garcia J et al.

Neurobiology of Disease, 2016

Pulling rabbits to reveal the secrets of the prion protein.

Fernandez-Funez P et al.

Communicative & Integrative Biology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."