Varaico: Literature-Extracted Genetic Variants

Gene:PRNP
Variant:p.D178V
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PRNP

NM_000311.5:p.D178V

Associated Papers

Effects of the pathological E200K mutation on human prion protein: A computational screening and molecular dynamics approach.

Gharemirshamloo FR et al.

Journal of Cellular Biochemistry, 2023

Atomic insight into prion disorder: An intricate detail gained by 0.5 μs molecular dynamics simulation of preventive G127V and deleterious D178V mutation in prion protein.

Gharemirshamlu FR et al.

Journal of Cellular Biochemistry, 2019

Molecular dynamics study of the dominant-negative E219K polymorphism in human prion protein.

Jahandideh S et al.

Journal of Biomolecular Structure & Dynamics, 2015

Systematic investigation of predicted effect of nonsynonymous SNPs in human prion protein gene: a molecular modeling and molecular dynamics study.

Jahandideh S et al.

Journal of Biomolecular Structure & Dynamics, 2014

One gene, two diseases and three conformations: molecular dynamics simulations of mutants of human prion protein at room temperature and elevated temperatures.

Shamsir MS et al.

Proteins, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."