Varaico: Literature-Extracted Genetic Variants

Gene:PRNP
Variant:p.E211K
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PRNP

NM_000311.5:p.E211K

Associated Papers

Canadian 2021 H-type Bovine Spongiform Encephalopathy case associated with a novel E211K polymorphism in prion protein gene.

Tahir W et al.

Prion, 2025

Identification of the Highly Polymorphic Prion Protein Gene (PRNP) in Frogs (Rana dybowskii).

Han CS et al.

Animals : an Open Access Journal From Mdpi, 2025

Low frequency of protective variants at regulatory region of PRNP gene indicating the genetically high risk of BSE in Ethiopian Bos indicus and Bos taurus africanus.

Teferedegn EY et al.

Animal Biotechnology, 2023

Potential Therapeutic Use of Stem Cells for Prion Diseases.

Zayed M et al.

Cells, 2023

Elevated E200K Somatic Mutation of the Prion Protein Gene (PRNP) in the Brain Tissues of Patients with Sporadic Creutzfeldt-Jakob Disease (CJD).

Won SY et al.

International Journal of Molecular Sciences, 2023

Short incubation periods of atypical H-type BSE in cattle with EK211 and KK211 prion protein genotypes after intracranial inoculation.

Cassmann ED et al.

Frontiers in Veterinary Science, 2023

First report of a strong association between genetic polymorphisms of the prion protein gene (PRNP) and susceptibility to chronic wasting disease in sika deer (Cervus nippon).

Roh IS et al.

Transboundary and Emerging Diseases, 2022

The First Evaluation of Proteinase K-Resistant Prion Protein (PrPSc) in Korean Appendix Specimens.

Won SY et al.

Medicina (kaunas, Lithuania), 2022

In-depth examination of PrPSc in Holstein cattle carrying the E211K somatic mutation of the bovine prion protein gene (PRNP).

Kim YC et al.

Transboundary and Emerging Diseases, 2022

Absence of proteinase K-resistant PrP in Korean Holstein cattle carrying potential bovine spongiform encephalopathy-related E211K somatic mutation.

Kim YC et al.

Transboundary and Emerging Diseases, 2022

Human prion protein: exploring the thermodynamic stability and structural dynamics of its pathogenic mutants.

Halder P et al.

Journal of Biomolecular Structure & Dynamics, 2022

Novel Polymorphisms and Genetic Characteristics of the Prion Protein Gene in Pheasants.

Kim KH et al.

Frontiers in Veterinary Science, 2022

Strong Association of the rs4986790 Single Nucleotide Polymorphism (SNP) of the Toll-Like Receptor 4 (TLR4) Gene with Human Immunodeficiency Virus (HIV) Infection: A Meta-Analysis.

Kim YC et al.

Genes, 2020

Polymorphisms of shadow of prion protein gene (SPRN) in Korean native cattle (Hanwoo) and Holstein cattle.

Kim YC et al.

Scientific Reports, 2020

First Report of the Potential Bovine Spongiform Encephalopathy (BSE)-Related Somatic Mutation E211K of the Prion Protein Gene (PRNP) in Cattle.

Won SY et al.

International Journal of Molecular Sciences, 2020

Genetic Factors in Mammalian Prion Diseases.

Mead S et al.

Annual Review of Genetics, 2019

Evaluation of EPAS1 variants for association with bovine congestive heart failure.

Heaton MP et al.

F1000research, 2019

Nucleotide and octapeptide-repeat variations of the prion protein coding gene (PRNP) in Anatolian, Murrah, and crossbred water buffaloes.

Yaman Y et al.

Tropical Animal Health and Production, 2018

Thermodynamic characterization for the denatured state of bovine prion protein and the BSE Associated variant E211K.

Hwang S et al.

Prion, 2018

Effects of a naturally occurring amino acid substitution in bovine PrP: a model for inherited prion disease in a natural host species.

Vrentas CE et al.

Bmc Research Notes, 2017

Lack of germline mutation at codon 211 of the prion protein gene (PRNP) in Korean native cattle - Short communication.

Kim YC et al.

Acta Veterinaria Hungarica, 2017

Insights into Mechanisms of Transmission and Pathogenesis from Transgenic Mouse Models of Prion Diseases.

Moreno JA et al.

Methods in Molecular Biology (clifton, N.j.), 2017

Molecular dynamics studies on the buffalo prion protein.

Zhang J et al.

Journal of Biomolecular Structure & Dynamics, 2016

A Comparison of Classical and H-Type Bovine Spongiform Encephalopathy Associated with E211K Prion Protein Polymorphism in Wild-Type and EK211 Cattle Following Intracranial Inoculation.

Moore SJ et al.

Frontiers in Veterinary Science, 2016

Using diverse U.S. beef cattle genomes to identify missense mutations in EPAS1, a gene associated with pulmonary hypertension.

Heaton MP et al.

F1000research, 2016

A Review of Selected Genes with Known Effects on Performance and Health of Cattle.

Casas E et al.

Frontiers in Veterinary Science, 2016

The prion protein gene polymorphisms associated with bovine spongiform encephalopathy susceptibility differ significantly between cattle and buffalo.

Zhao H et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2015

Genetics of Prion Disease in Cattle.

Murdoch BM et al.

Bioinformatics and Biology Insights, 2015

Genetic diversity in the prion protein gene (PRNP) of domestic cattle and water buffaloes in Vietnam, Indonesia and Thailand.

Uchida L et al.

The Journal of Veterinary Medical Science, 2014

Spontaneous generation of infectious prion disease in transgenic mice.

Torres JM et al.

Emerging Infectious Diseases, 2013

Discriminant analysis of prion sequences for prediction of susceptibility.

Lee JH et al.

Experimental & Molecular Medicine, 2013

PRNP gene variation in Pakistani cattle and buffaloes.

Imran M et al.

Gene, 2012

PRNP and SPRN genes polymorphism in atypical bovine spongiform encephalopathy cases diagnosed in Polish cattle.

Gurgul A et al.

Journal of Applied Genetics, 2012

Sequence variations of the bovine prion protein gene (PRNP) in native Korean Hanwoo cattle.

Choi S et al.

Journal of Veterinary Science, 2012

Genetic variability of the coding region for the prion protein gene (PRNP) in gayal (Bos frontalis).

Xi D et al.

Molecular Biology Reports, 2012

Clinical and pathologic features of H-type bovine spongiform encephalopathy associated with E211K prion protein polymorphism.

Greenlee JJ et al.

Plos One, 2012

Bovine spongiform encephalopathy associated insertion/deletion polymorphisms of the prion protein gene in the four beef cattle breeds from North China.

Zhu XY et al.

Genome, 2011

Polymorphism of the prion protein gene (PRNP) in two Chinese indigenous cattle breeds.

Qin LH et al.

Molecular Biology Reports, 2011

Genetic Creutzfeldt-Jakob disease and fatal familial insomnia: insights into phenotypic variability and disease pathogenesis.

Capellari S et al.

Acta Neuropathologica, 2011

Atypical prion diseases in humans and animals.

Tranulis MA et al.

Topics in Current Chemistry, 2011

PRNP haplotype associated with classical BSE incidence in European Holstein cattle.

Murdoch BM et al.

Plos One, 2010

Prion protein gene (PRNP) polymorphisms in native Chinese cattle.

Zhao H et al.

Genome, 2010

BSE case associated with prion protein gene mutation.

Richt JA et al.

Plos Pathogens, 2008

Identification of a heritable polymorphism in bovine PRNP associated with genetic transmissible spongiform encephalopathy: evidence of heritable BSE.

Nicholson EM et al.

Plos One, 2008

Prevalence of the prion protein gene E211K variant in U.S. cattle.

Heaton MP et al.

Bmc Veterinary Research, 2008

A sequencing strategy for identifying variation throughout the prion gene of BSE-affected cattle.

Clawson ML et al.

Bmc Research Notes, 2008

Association of a bovine prion gene haplotype with atypical BSE.

Clawson ML et al.

Plos One, 2008

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