Associated Papers
De novo nucleotide biosynthetic pathway and cancer.
Chen J et al.
Genes & Diseases, 2023
CRISPR/Cas9-Mediated Induction of Relapse-Specific NT5C2 and PRPS1 Mutations Confers Thiopurine Resistance as a Relapsed Lymphoid Leukemia Model.
Nguyen TTT et al.
Molecular Pharmacology, 2023
Promising genes and variants to reduce chemotherapy adverse effects in acute lymphoblastic leukemia.
Bárcenas-López DA et al.
Translational Oncology, 2021
Increase of PRPP enhances chemosensitivity of PRPS1 mutant acute lymphoblastic leukemia cells to 5-Fluorouracil.
Wang D et al.
Journal of Cellular and Molecular Medicine, 2018
Clinical manifestations and molecular aspects of phosphoribosylpyrophosphate synthetase superactivity in females.
Zikánová M et al.
Rheumatology (oxford, England), 2018
Negative feedback-defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL.
Li B et al.
Nature Medicine, 2015
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