Associated Papers
Evolutionary expansion of polyaspartate motif in the activation peptide of mouse cationic trypsinogen limits autoactivation and protects against pancreatitis.
Orekhova A et al.
American Journal of Physiology. Gastrointestinal and Liver Physiology, 2021
Engineering mouse cationic trypsinogen for rapid and selective activation by cathepsin B.
Demcsák A et al.
Scientific Reports, 2019
A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation.
Geisz A et al.
Nature Communications, 2018
The tetra-aspartate motif in the activation peptide of human cationic trypsinogen is essential for autoactivation control but not for enteropeptidase recognition.
Nemoda Z et al.
The Journal of Biological Chemistry, 2005
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