Varaico: Literature-Extracted Genetic Variants

Gene:PRSS2
Variant:p.D105G
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PRSS2

NM_002770.4:p.D105G

Associated Papers

Host genetic variants in sepsis risk: a field synopsis and meta-analysis.

Lu H et al.

Critical Care (london, England), 2019

30683156 (PubMed )
Supplement: 13054_2019_2313_MOESM6_ESM.xls › Sheet1

Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.

Yaseen S et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2017

Molecular defects in the mannose binding lectin pathway in dermatological disease: Case report and literature review.

Miller C et al.

Clinical and Molecular Allergy : Cma, 2010

Mannose-binding lectin and mannose-binding lectin-associated serine protease 2 in susceptibility, severity, and outcome of pneumonia in adults.

Garcia-Laorden MI et al.

The Journal of Allergy and Clinical Immunology, 2008

Deficiency of mannose-binding lectin-associated serine protease-2 associated with increased risk of fever and neutropenia in pediatric cancer patients.

Schlapbach LJ et al.

The Pediatric Infectious Disease Journal, 2007

The influence of innate immunity gene receptors polymorphisms in renal transplant infections.

Cervera C et al.

Transplantation, 2007

The mannan-binding lectin pathway and lung disease in cystic fibrosis--disfunction of mannan-binding lectin-associated serine protease 2 (MASP-2) may be a major modifier.

Olesen HV et al.

Clinical Immunology (orlando, Fla.), 2006

Low clinical penetrance of mannose-binding lectin-associated serine protease 2 deficiency.

García-Laorden MI et al.

The Journal of Allergy and Clinical Immunology, 2006

Novel MASP2 variants detected among North African and Sub-Saharan individuals.

Lozano F et al.

Tissue Antigens, 2005

Functional MASP2 single nucleotide polymorphism plays no role in psoriasis.

Stover C et al.

The British Journal of Dermatology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."