Varaico: Literature-Extracted Genetic Variants

Gene:PRSS2
Variant:p.S195A
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PRSS2

NM_002770.4:p.S195A

Associated Papers

Substrate specificity of human chymotrypsin-like protease (CTRL) characterized by phage display-selected small-protein inhibitors.

Németh BZ et al.

Pancreatology : Official Journal of the International Association of Pancreatology (iap) ... [et Al.], 2023

Arg236 in human chymotrypsin B2 (CTRB2) is a key determinant of high enzyme activity, trypsinogen degradation capacity, and protection against pancreatitis.

Németh BZ et al.

Biochimica Et Biophysica Acta. Proteins and Proteomics, 2022

Multiple domains of MASP-2, an initiating complement protease, are required for interaction with its substrate C4.

Duncan RC et al.

Molecular Immunology, 2012

The energetic cost of induced fit catalysis: Crystal structures of trypsinogen mutants with enhanced activity and inhibitor affinity.

Pasternak A et al.

Protein Science : a Publication of the Protein Society, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."