Associated Papers
AZP2006 (Ezeprogind®): a Promising New Drug Candidate in the Battle Against Neurodegenerative Diseases.
Verwaerde P et al.
Chemmedchem, 2025
Mitochondrial Dysfunction due to Novel COQ8A Variation with Poor Response to CoQ10 Treatment: A Comprehensive Study and Review of Literatures.
Wang J et al.
Cerebellum (london, England), 2024
The Enigma of Tau Protein Aggregation: Mechanistic Insights and Future Challenges.
Zheng H et al.
International Journal of Molecular Sciences, 2024
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature.
Cascella R et al.
Annals of Medicine, 2023
Targeted brain-specific tauopathy compromises peripheral skeletal muscle integrity and function.
Alava B et al.
Biorxiv : the Preprint Server for Biology, 2023
Glaucoma as a Tauopathy-Is It the Missing Piece in the Glaucoma Puzzle?
Passaro ML et al.
Journal of Clinical Medicine, 2023
Anti-tau antibodies targeting a conformation-dependent epitope selectively bind seeds.
Hitt BD et al.
The Journal of Biological Chemistry, 2023
FSH and ApoE4 contribute to Alzheimer's disease-like pathogenesis via C/EBPβ/δ-secretase in female mice.
Xiong J et al.
Nature Communications, 2023
Monoclonal antibody Y01 prevents tauopathy progression induced by lysine 280-acetylated tau in cell and mouse models.
Song HL et al.
The Journal of Clinical Investigation, 2023
Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model.
Williams JB et al.
Nature Communications, 2023
Quantitative super-resolution imaging of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies.
Morten MJ et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022
Tau seeding in cases of multiple sclerosis.
LaCroix MS et al.
Acta Neuropathologica Communications, 2022
Seed-competent tau monomer initiates pathology in a tauopathy mouse model.
Mirbaha H et al.
The Journal of Biological Chemistry, 2022
Synaptic Localisation of Tau.
Hanger DP et al.
Advances in Experimental Medicine and Biology, 2019
Cellular Prion Protein Mediates the Disruption of Hippocampal Synaptic Plasticity by Soluble Tau In Vivo.
Ondrejcak T et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2018
Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau.
Courade JP et al.
Acta Neuropathologica, 2018
In Vivo Tau Imaging for a Diagnostic Platform of Tauopathy Using the rTg4510 Mouse Line.
Sahara N et al.
Frontiers in Neurology, 2017
Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations.
Iovino M et al.
Brain : a Journal of Neurology, 2015
Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice.
Garringer HJ et al.
Plos One, 2013
Dietary cholesterol and its effect on tau protein: a study in apolipoprotein E-deficient and P301L human tau mice.
Glöckner F et al.
Journal of Neuropathology and Experimental Neurology, 2011
Hallmark cellular pathology of Alzheimer's disease induced by mutant human tau expression in cultured Aplysia neurons.
Shemesh OA et al.
Acta Neuropathologica, 2010
Axonal degeneration induced by targeted expression of mutant human tau in oligodendrocytes of transgenic mice that model glial tauopathies.
Higuchi M et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2005
Frontotemporal dementia and tauopathy.
Yoshiyama Y et al.
Current Neurology and Neuroscience Reports, 2001
Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations.
Goedert M et al.
Journal of Neurochemistry, 2000