Associated Papers
Intrinsic resistance to RAS inhibitors is driven by dysregulation of KRAS degradation.
Ivanisevic T et al.
Nature Communications, 2025
Evaluation of SNaPshot and Sanger sequencing for the detection of KRAS and NRAS mutations in a sample of Venezuelan patients with colorectal cancer.
Rodríguez-Carrascal D et al.
Ecancermedicalscience, 2024
Genetics of brain arteriovenous malformations and cerebral cavernous malformations.
Hongo H et al.
Journal of Human Genetics, 2023
In silico comparative analysis of KRAS mutations at codons 12 and 13: Structural modifications of P-Loop, switch I&II regions preventing GTP hydrolysis.
Gerber M et al.
Computers in Biology and Medicine, 2022
Development and Validation of Targeted Gene Sequencing Panel Based Companion Diagnostic for Korean Patients with Solid Tumors.
Min BJ et al.
Cancers, 2021
GNAS mutation is a frequent event in pancreatic intraductal papillary mucinous neoplasms and associated adenocarcinomas.
Hosoda W et al.
Virchows Archiv : an International Journal of Pathology, 2015
KRAS and guanine nucleotide-binding protein mutations in pancreatic juice collected from the duodenum of patients at high risk for neoplasia undergoing endoscopic ultrasound.
Eshleman JR et al.
Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association, 2015
Molecular profiling of infiltrating urothelial carcinoma of bladder and nonbladder origin.
Millis SZ et al.
Clinical Genitourinary Cancer, 2015
Ubiquitin proteasomal pathway mediated degradation of p53 in melanoma.
Anwar A et al.
Archives of Biochemistry and Biophysics, 2011
Stimulation of actin polymerization by vacuoles via Cdc42p-dependent signaling.
Isgandarova S et al.
The Journal of Biological Chemistry, 2007
Hyperactivation of the RAS signaling pathway in myelodysplastic syndrome with AML1/RUNX1 point mutations.
Niimi H et al.
Leukemia, 2006
GJB2 mutations and degree of hearing loss: a multicenter study.
Snoeckx RL et al.
American Journal of Human Genetics, 2005
Conformational states of Ras complexed with the GTP analogue GppNHp or GppCH2p: implications for the interaction with effector proteins.
Spoerner M et al.
Biochemistry, 2005
Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration.
Grimsley CM et al.
The Journal of Biological Chemistry, 2004
Fibrinogen Saint-Germain I: a case of the heterozygous Aalpha GLY 12 --> VAL fibrinogen variant.
Mathonnet F et al.
Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis, 2002
RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao.
Traver S et al.
The Biochemical Journal, 2000
Mutant Rac1B expression in Dictyostelium: effects on morphology, growth, endocytosis, development, and the actin cytoskeleton.
Palmieri SJ et al.
Cell Motility and the Cytoskeleton, 2000
Hydrolysis of GTP by the alpha-chain of Gs and other GTP binding proteins.
Bourne HR et al.
Proteins, 1989