Varaico: Literature-Extracted Genetic Variants

Gene:PSEN1
Variant:p.S102A
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PSEN1

NM_000021.4:p.S102A

Associated Papers

Inhibition of γ-secretase activity by a monoclonal antibody against the extracellular hydrophilic loop of presenilin 1.

Takagi-Niidome S et al.

Biochemistry, 2013

Hydrophilic loop 1 of Presenilin-1 and the APP GxxxG transmembrane motif regulate γ-secretase function in generating Alzheimer-causing Aβ peptides.

Liu L et al.

The Journal of Biological Chemistry, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."