Associated Papers
Enzyme-substrate interface targeting by imidazole-based γ-secretase modulators activates γ-secretase and stabilizes its interaction with APP.
Petit D et al.
The Embo Journal, 2022
36121025 (PubMed )
Supplement: EMBJ-41-e111084-s001.pdf
A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline.
Luo R et al.
Signal Transduction and Targeted Therapy, 2021
34465723 (PubMed )
Supplement: 41392_2021_748_MOESM1_ESM.docx
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