Associated Papers
Mutational re-modeling of di-aspartyl intramembrane proteases: uncoupling physiologically-relevant activities from those associated with Alzheimer's disease.
Grigorenko AP et al.
Oncotarget, 2017
A ubiquitin-binding CUE domain in presenilin-1 enables interaction with K63-linked polyubiquitin chains.
Duggan SP et al.
Febs Letters, 2015
Identification of gamma-secretase inhibitor potency determinants on presenilin.
Zhao B et al.
The Journal of Biological Chemistry, 2008
Functional domains in presenilin 1: the Tyr-288 residue controls gamma-secretase activity and endoproteolysis.
Laudon H et al.
The Journal of Biological Chemistry, 2004
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