Varaico: Literature-Extracted Genetic Variants

Gene:PSEN1
Variant:p.S401R
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PSEN1

NM_000021.4:p.S401R

Associated Papers

Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate.

Twomey C et al.

Febs Letters, 2006

Glycogen synthase kinase-3beta regulates presenilin 1 C-terminal fragment levels.

Kirschenbaum F et al.

The Journal of Biological Chemistry, 2001

Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling.

Kirschenbaum F et al.

The Journal of Biological Chemistry, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."