Varaico: Literature-Extracted Genetic Variants

Gene:PSEN1
Variant:p.N405T
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PSEN1

NM_000021.4:p.N405T

Associated Papers

Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations.

Wanngren J et al.

Febs Open Bio, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."