Varaico: Literature-Extracted Genetic Variants

Gene:PTAFR
Variant:p.D289A
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PTAFR

NM_000952.5:p.D289A

Associated Papers

Janus kinase 2 activation by the platelet-activating factor receptor (PAFR): roles of Tyk2 and PAFR C terminus.

Lukashova V et al.

Journal of Immunology (baltimore, Md. : 1950), 2003

Agonist-induced internalization of the platelet-activating factor receptor is dependent on arrestins but independent of G-protein activation. Role of the C terminus and the (D/N)PXXY motif.

Chen Z et al.

The Journal of Biological Chemistry, 2002

Selective modulation of wild type receptor functions by mutants of G-protein-coupled receptors.

Le Gouill C et al.

The Journal of Biological Chemistry, 1999

Structural and functional requirements for agonist-induced internalization of the human platelet-activating factor receptor.

Le Gouill C et al.

The Journal of Biological Chemistry, 1997

Alanine exchanges of polar amino acids in the transmembrane domains of a platelet-activating factor receptor generate both constitutively active and inactive mutants.

Ishii I et al.

The Journal of Biological Chemistry, 1997

Identification of transmembrane domain residues determinant in the structure-function relationship of the human platelet-activating factor receptor by site-directed mutagenesis.

Parent JL et al.

The Journal of Biological Chemistry, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."