Associated Papers
Fumarate inhibits PTEN to promote tumorigenesis and therapeutic resistance of type2 papillary renal cell carcinoma.
Ge X et al.
Molecular Cell, 2022
Cigarette smoke extract amplifies NADPH oxidase-dependent ROS production to inactivate PTEN by oxidation in BEAS-2B cells.
Cai B et al.
Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association, 2021
Analyzing aggregation propensities of clinically relevant PTEN mutants: a new culprit in pathogenesis of cancer and other PTENopathies.
Palumbo E et al.
Journal of Biomolecular Structure & Dynamics, 2020
31232187 (PubMed )
Supplement: supplement_1.zip › Supplement_S4_mutants_nochange.xlsx › Mutants_no_change
15-Deoxy-Δ12,14-prostaglandin J2 activates PI3K-Akt signaling in human breast cancer cells through covalent modification of the tumor suppressor PTEN at cysteine 136.
Suh J et al.
Cancer Letters, 2018
Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care.
Kong SL et al.
Oncotarget, 2017
28978093 (PubMed )
Supplement: oncotarget-08-68026-s002.xlsx › Table_S5
AIF inhibits tumor metastasis by protecting PTEN from oxidation.
Shen SM et al.
Embo Reports, 2015
Endogenous S-sulfhydration of PTEN helps protect against modification by nitric oxide.
Ohno K et al.
Biochemical and Biophysical Research Communications, 2015
Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium.
Nguyen HN et al.
Oncogene, 2014
Guggulsterone induces heme oxygenase-1 expression through activation of Nrf2 in human mammary epithelial cells: PTEN as a putative target.
Almazari I et al.
Carcinogenesis, 2012
Tyr740 and Tyr751 residues of platelet-derived growth factor beta receptor are responsible for the redox regulation of phosphatase and tensin homolog in the cells stimulated with platelet-derived growth factor.
Kim I et al.
Redox Report : Communications in Free Radical Research, 2011
Reversible inactivation of the tumor suppressor PTEN by H2O2.
Lee SR et al.
The Journal of Biological Chemistry, 2002
Select a paper to view details