Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.D107N
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PTEN

NM_000314.8:p.D107N

Associated Papers

First Screening For Germline Variations In Exon 5 PTEN Gene and Their Contribution to Triple Negative Breast Cancer in Eastern Algeria.

Haddad S et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2025

Comprehensive computational analysis of deleterious nsSNPs in PTEN gene for structural and functional insights.

Sharma D et al.

Molecular Biology Research Communications, 2025

Mosaicism in Tumor Suppressor Gene Syndromes: Prevalence, Diagnostic Strategies, and Transmission Risk.

Chen JL et al.

Annual Review of Genomics and Human Genetics, 2022

36044908 (PubMed )
Supplement: gg23-giannikou_suptable1.xlsx › PTEN

Comprehensive characterization of PTEN mutational profile in a series of 34,129 colorectal cancers.

Serebriiskii IG et al.

Nature Communications, 2022

35338148 (PubMed )
Supplement: 41467_2022_29227_MOESM6_ESM.xlsx › Supplemenraty_Data_3

Analyzing aggregation propensities of clinically relevant PTEN mutants: a new culprit in pathogenesis of cancer and other PTENopathies.

Palumbo E et al.

Journal of Biomolecular Structure & Dynamics, 2020

31232187 (PubMed )
Supplement: supplement_1.zip › Supplement_S4_mutants_nochange.xlsx › Mutants_no_change

Prediction of functionally significant single nucleotide polymorphisms in PTEN tumor suppressor gene: An in silico approach.

Khan I et al.

Biotechnology and Applied Biochemistry, 2017

Prediction and Analysis of Breast Cancer Related Deleterious Non-Synonymous Single Nucleotide Polymorphisms in the PTEN Gene.

Naidu CK et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2016

Phase II clinical and exploratory biomarker study of dacomitinib in patients with recurrent and/or metastatic squamous cell carcinoma of head and neck.

Kim HS et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2015

A new insight into structural and functional impact of single-nucleotide polymorphisms in PTEN gene.

George Priya Doss C et al.

Cell Biochemistry and Biophysics, 2013

Epidemiology, major risk factors and genetic predisposition for breast cancer in the Pakistani population.

Shaukat U et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2013

Association of sporadic breast cancer with PTEN/MMAC1/TEP1 promoter hypermethylation.

Sadeq V et al.

Medical Oncology (northwood, London, England), 2011

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt

Genetic changes in the PTEN gene and their association with breast cancer in Pakistan.

Baig RM et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2011

Pharmacogenomic profiling of the PI3K/PTEN pathway in sporadic breast cancer.

Nassiri I et al.

Iranian Biomedical Journal, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."