Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.I135M
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PTEN

NM_000314.8:p.I135M

Associated Papers

A scalable Drosophila assay for clinical interpretation of human PTEN variants in suppression of PI3K/AKT induced cellular proliferation.

Ganguly P et al.

Plos Genetics, 2021

34492006 (PubMed )
Supplement: pgen.1009774.s010.xlsx › Annotation_of_PTEN_variants

Analyzing aggregation propensities of clinically relevant PTEN mutants: a new culprit in pathogenesis of cancer and other PTENopathies.

Palumbo E et al.

Journal of Biomolecular Structure & Dynamics, 2020

31232187 (PubMed )
Supplement: supplement_1.zip › Supplement_S6_decrease_aggreg_analysis.xlsx › Intrinsic_Disorder_all

Cell-Free DNA and Neuromediators in Detecting Aggressive Variant Prostate Cancer.

von Hardenberg J et al.

Oncology Research and Treatment, 2018

The relationship between microsatellite instability and PTEN gene mutations in endometrial cancer.

Bilbao C et al.

International Journal of Cancer, 2006

Molecular alterations associated with cyclin D1 overexpression in endometrial cancer.

Moreno-Bueno G et al.

International Journal of Cancer, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."