Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.Y138F
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PTEN

NM_000314.8:p.Y138F

Associated Papers

Pleiotropic tumor suppressive functions of PTEN missense mutations during gliomagenesis.

Jun HJ et al.

Iscience, 2024

Comprehensive characterization of PTEN mutational profile in a series of 34,129 colorectal cancers.

Serebriiskii IG et al.

Nature Communications, 2022

35338148 (PubMed )
Supplement: 41467_2022_29227_MOESM6_ESM.xlsx › Supplemenraty_Data_3

The INPP4B paradox: Like PTEN, but different.

Hamila SA et al.

Advances in Biological Regulation, 2021

Stage IV Colorectal Cancer Patients with High Risk Mutation Profiles Survived 16 Months Longer with Individualized Therapies.

Hendricks A et al.

Cancers, 2020

32046290 (PubMed )
Supplement: cancers-12-00393-s001.zip › cancers-698395-2.revision.supplementary_materials › SuppTables_S1-S7_.xlsx › S5_American_patients_mutations

PTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7.

Shinde SR et al.

Nature Communications, 2016

WWP2 is an E3 ubiquitin ligase for PTEN.

Maddika S et al.

Nature Cell Biology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."