Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.K163R
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PTEN

NM_000314.8:p.K163R

Associated Papers

De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function.

Wan J et al.

Cell Reports, 2023

Clinical significance of molecular subgroups of polymorphous low-grade neuroepithelial tumor of the young (PLNTY): A small single institutional case series and integrated analysis.

Vuong HG et al.

Pathology, Research and Practice, 2023

Classification of PTEN missense VUS through exascale simulations.

Sinha S et al.

Briefings in Bioinformatics, 2023

Targeting PTEN Regulation by Post Translational Modifications.

González-García A et al.

Cancers, 2022

Utilisation of semiconductor sequencing for the detection of predictive biomarkers in glioblastoma.

Williams G et al.

Plos One, 2022

35324914 (PubMed )
Supplement: pone.0245817.s005.pdf

Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis.

Sisti F et al.

Science Signaling, 2018

Prevalence and spectrum of AKT1, PIK3CA, PTEN and TP53 somatic mutations in Chinese breast cancer patients.

Li G et al.

Plos One, 2018

Synergistic antitumor effects of the combined treatment with an HDAC6 inhibitor and a COX-2 inhibitor through activation of PTEN.

Zhang G et al.

Oncology Reports, 2017

PTEN activation through K163 acetylation by inhibiting HDAC6 contributes to tumour inhibition.

Meng Z et al.

Oncogene, 2016

Molecular genetic alterations in glioblastomas with oligodendroglial component.

Kraus JA et al.

Acta Neuropathologica, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."