Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.L186M
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PTEN

NM_000314.8:p.L186M

Associated Papers

Genetic alterations of PTEN in human melanoma.

Aguissa-Touré AH et al.

Cellular and Molecular Life Sciences : Cmls, 2012

Osteopontin is a downstream effector of the PI3-kinase pathway in melanomas that is inversely correlated with functional PTEN.

Packer L et al.

Carcinogenesis, 2006

PTEN inactivation is rare in melanoma tumours but occurs frequently in melanoma cell lines.

Pollock PM et al.

Melanoma Research, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."