Associated Papers
Epilepsy and Developmental Delay in Pediatric Patients With PTEN Variants and a Literature Review.
Li Q et al.
Pediatric Neurology, 2025
Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity.
Shah SM et al.
Cancer Research Communications, 2024
38282550 (PubMed )
Supplement: crc-23-0312-s02.xlsx › Fig3B_EC_data
Synthetic lethal approaches to target cancers with loss of PTEN function.
Ertay A et al.
Genes & Diseases, 2023
Emerging role of PTEN loss in evasion of the immune response to tumours.
Vidotto T et al.
British Journal of Cancer, 2020
Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers.
Fougner C et al.
Breast Cancer Research : Bcr, 2019
31366361 (PubMed )
Supplement: 13058_2019_1170_MOESM5_ESM.xlsx › MPADMBA_muts_in_COSMIC_genes
Hidden association of Cowden syndrome, PTEN mutation and meningioma frequency.
Yakubov E et al.
Oncoscience, 2016
27489861 (PubMed )
Supplement: oncoscience-03-149-s001.pdf
PTEN C-terminal deletion causes genomic instability and tumor development.
Sun Z et al.
Cell Reports, 2014
Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53.
He X et al.
Human Molecular Genetics, 2011
Genetic and phenotypic heterogeneity in the PTEN hamartoma tumour syndrome.
Orloff MS et al.
Oncogene, 2008
Essential role for nuclear PTEN in maintaining chromosomal integrity.
Shen WH et al.
Cell, 2007
Germline PTEN mutations are rare and highly penetrant.
Rustad CF et al.
Hereditary Cancer in Clinical Practice, 2006
Genetic alterations and aberrant expression of genes related to the phosphatidyl-inositol-3'-kinase/protein kinase B (Akt) signal transduction pathway in glioblastomas.
Knobbe CB et al.
Brain Pathology (zurich, Switzerland), 2003
Comprehensive analysis of genomic alterations in gliosarcoma and its two tissue components.
Actor B et al.
Genes, Chromosomes & Cancer, 2002
Inherited mutations in PTEN that are associated with breast cancer, cowden disease, and juvenile polyposis.
Lynch ED et al.
American Journal of Human Genetics, 1997
Select a paper to view details