Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.V216L
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PTEN

NM_000314.8:p.V216L

Associated Papers

Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment.

Berezovsky A et al.

Plos One, 2025

Analyzing aggregation propensities of clinically relevant PTEN mutants: a new culprit in pathogenesis of cancer and other PTENopathies.

Palumbo E et al.

Journal of Biomolecular Structure & Dynamics, 2020

31232187 (PubMed )
Supplement: supplement_1.zip › Supplement_S4_mutants_nochange.xlsx › Mutants_no_change

Targeted deep sequencing from multiple sources demonstrates increased NOTCH1 alterations in lung cancer patient plasma.

Liao Y et al.

Cancer Medicine, 2019

31369215 (PubMed )
Supplement: CAM4-8-5673-s008.xlsx › Supplementary_Table_S5

Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors.

Yachida S et al.

The American Journal of Surgical Pathology, 2012

Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay.

Han SY et al.

Cancer Research, 2000

10866302 (PubMed )
Supplement: 00085472can042935-sup-supplementary_table_1.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."