Associated Papers
PTEN-mediated dephosphorylation of 53BP1 confers cellular resistance to DNA damage in cancer cells.
He J et al.
Molecular Oncology, 2024
Molecular dynamic simulation and functional analysis of pathogenic PTEN mutations in glioblastoma.
Cetintas VB et al.
Journal of Biomolecular Structure & Dynamics, 2023
TRIM25 activates AKT/mTOR by inhibiting PTEN via K63-linked polyubiquitination in non-small cell lung cancer.
He YM et al.
Acta Pharmacologica Sinica, 2022
The deubiquitinase USP10 restores PTEN activity and inhibits non-small cell lung cancer cell proliferation.
He Y et al.
The Journal of Biological Chemistry, 2021
Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.
Nagasawa S et al.
Communications Biology, 2021
33795819 (PubMed )
Supplement: 42003_2021_1959_MOESM5_ESM.xlsx › CaseA
Autism-associated PTEN missense mutation leads to enhanced nuclear localization and neurite outgrowth in an induced pluripotent stem cell line.
Wong CW et al.
The Febs Journal, 2020
The Loss of Nuclear PTEN Increases Tumorigenesis in a Preclinical Mouse Model for Hepatocellular Carcinoma.
Kato T et al.
Iscience, 2020
33083717 (PubMed )
Supplement: mmc1.pdf
The Impact of Genetic Variants on PTEN Molecular Functions and Cellular Phenotypes.
Hasle N et al.
Cold Spring Harbor Perspectives in Medicine, 2019
PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.
Zhang J et al.
Cancer Discovery, 2019
PIASxα ligase enhances SUMO1 modification of PTEN protein as a SUMO E3 ligase.
Wang W et al.
The Journal of Biological Chemistry, 2014
SUMO, PTEN and Tumor Suppression.
Matunis MJ et al.
Pigment Cell & Melanoma Research, 2012
SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane.
Huang J et al.
Nature Communications, 2012
The Nuclear Face of PTEN: Implications in Cancer Prognosis and Targeted Therapy.
Ghosh MK et al.
Biofactors (oxford, England), 0
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