Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.Y315F
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PTEN

NM_000314.8:p.Y315F

Associated Papers

The Impact of Genetic Variants on PTEN Molecular Functions and Cellular Phenotypes.

Hasle N et al.

Cold Spring Harbor Perspectives in Medicine, 2019

Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland.

Jones CE et al.

Neoplasia (new York, N.y.), 2019

Multiplex assessment of protein variant abundance by massively parallel sequencing.

Matreyek KA et al.

Nature Genetics, 2018

29785012 (PubMed )
Supplement: NIHMS956040-supplement-2.doc

Rak functions as a tumor suppressor by regulating PTEN protein stability and function.

Yim EK et al.

Cancer Cell, 2009

Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity.

Koul D et al.

Oncogene, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."