Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.Y336F
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PTEN

NM_000314.8:p.Y336F

Associated Papers

Mechanism of PRL2 phosphatase-mediated PTEN degradation and tumorigenesis.

Li Q et al.

Proceedings of the National Academy of Sciences of the United States of America, 2020

Analyzing aggregation propensities of clinically relevant PTEN mutants: a new culprit in pathogenesis of cancer and other PTENopathies.

Palumbo E et al.

Journal of Biomolecular Structure & Dynamics, 2020

31232187 (PubMed )
Supplement: supplement_1.zip › Supplement_S4_mutants_nochange.xlsx › Mutants_no_change

Rak functions as a tumor suppressor by regulating PTEN protein stability and function.

Yim EK et al.

Cancer Cell, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."