Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.T348I
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PTEN

NM_000314.8:p.T348I

Associated Papers

Analyzing aggregation propensities of clinically relevant PTEN mutants: a new culprit in pathogenesis of cancer and other PTENopathies.

Palumbo E et al.

Journal of Biomolecular Structure & Dynamics, 2020

31232187 (PubMed )
Supplement: supplement_1.zip › Supplement_S4_mutants_nochange.xlsx › Mutants_no_change

Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer.

Smith IN et al.

Proteins, 2016

Genomic Rearrangements of PTEN in Prostate Cancer.

Phin S et al.

Frontiers in Oncology, 2013

A new insight into structural and functional impact of single-nucleotide polymorphisms in PTEN gene.

George Priya Doss C et al.

Cell Biochemistry and Biophysics, 2013

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt

In vivo functional analysis of the counterbalance of hyperactive phosphatidylinositol 3-kinase p110 catalytic oncoproteins by the tumor suppressor PTEN.

Andrés-Pons A et al.

Cancer Research, 2007

The tumour suppressor PTEN: involvement of a tumour suppressor candidate protein in PTEN turnover.

Maehama T et al.

Biochemical Society Transactions, 2004

Mutations of the human PTEN gene.

Bonneau D et al.

Human Mutation, 2000

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region.

Georgescu MM et al.

Proceedings of the National Academy of Sciences of the United States of America, 1999

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