Associated Papers
Impaired nuclear PTEN function drives macrocephaly, lymphadenopathy and late-onset cancer in PTEN hamartoma tumour syndrome.
Tibarewal P et al.
Disease Models & Mechanisms, 2026
Nuclear PTEN's Functions in Suppressing Tumorigenesis: Implications for Rare Cancers.
Langdon CG
Biomolecules, 2023
The HECT family of E3 ubiquitin ligases and PTEN.
Song MS et al.
Seminars in Cancer Biology, 2022
Generating a new mouse model for nuclear PTEN deficiency by a single K13R mutation.
Kato T et al.
Genes to Cells : Devoted to Molecular & Cellular Mechanisms, 2021
Nuclear PTEN deficiency and heterozygous PTEN loss have distinct impacts on brain and lymph node size.
Igarashi A et al.
Biochemical and Biophysical Research Communications, 2021
Nuclear PTEN and p53 suppress stress-induced liver cancer through distinct mechanisms.
Kato T et al.
Biochemical and Biophysical Research Communications, 2021
The Loss of Nuclear PTEN Increases Tumorigenesis in a Preclinical Mouse Model for Hepatocellular Carcinoma.
Kato T et al.
Iscience, 2020
Nuclear PTEN deficiency causes microcephaly with decreased neuronal soma size and increased seizure susceptibility.
Igarashi A et al.
The Journal of Biological Chemistry, 2018
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