Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.T398A
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PTEN

NM_000314.8:p.T398A

Associated Papers

PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.

Zhang J et al.

Cancer Discovery, 2019

Grb2 binds to PTEN and regulates its nuclear translocation to maintain the genomic stability in DNA damage response.

Hou B et al.

Cell Death & Disease, 2019

Precise definition of PTEN C-terminal epitopes and its implications in clinical oncology.

Mingo J et al.

Npj Precision Oncology, 2019

Characterization of nuclear PTEN and its post translational modifications.

Ho J et al.

Methods (san Diego, Calif.), 2015

ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells.

Chen JH et al.

Autophagy, 2015

Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress.

Bassi C et al.

Science (new York, N.y.), 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."