Varaico: Literature-Extracted Genetic Variants

Gene:PTEN
Variant:p.T401A
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PTEN

NM_000314.8:p.T401A

Associated Papers

PTEN is both an activator and a substrate of chaperone-mediated autophagy.

Zhang KK et al.

The Journal of Cell Biology, 2023

PTEN-PDZ domain interactions: binding of PTEN to PDZ domains of PTPN13.

Sotelo NS et al.

Methods (san Diego, Calif.), 2015

Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) is required for the estradiol-dependent increase of phosphatase and tensin homolog (PTEN) protein expression.

Yang L et al.

Endocrinology, 2011

Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.

Valiente M et al.

The Journal of Biological Chemistry, 2005

The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation.

Torres J et al.

The Journal of Biological Chemistry, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."